When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

Mammalian cell gene editing has extensively used RNA-guided CRISPR-Cas systems, which have shown great promise in the treatment of genetic disorders. Class II Cas9 and ... T or A) PAM sequence ...

With vasa-Cas9, high efficiency and self-limiting suppression was achieved. Applying the CRISPR-Cas9 system to edit high GC content genomes has been challenging due to its high off-target activity.

Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.

Stanford researchers introduced affordable gene-editing kits ready for the classroom, aiming to make the field more accessible for high school students.