Subsequently, by extensively screening thousands of proteins in a cell surface protein database, they identified transferrin receptor 1 (TfR1) as highly expressed in NPC and closely associated ...

JCR’s proprietary J-Brain Cargo technology relies on a transferrin receptor-targeting antibody to deliver effector proteins into the CNS (Fig. 1). By binding to transferrin receptors on BBB ...

Inatherys SAS recently presented preclinical data for INA-03, an anti-transferrin receptor (TfR1/CD71) antibody-drug conjugate (ADC), being developed for the treatment of triple-negative breast cancer ...

“We are developing peptide and nanobody vectors that bind to well-defined receptors expressed by cells lining the BBB that facilitate the entry of essential nutrients such as ...