Gallbladder problems are a common complication in individuals with sickle cell disease. These issues often arise due to the breakdown of red blood cells and the subsequent formation of gallstones or ...

Sickle cell anaemia is a genetic blood disorder characterised by the production of an abnormal haemoglobin, known as ...

Our fundamental challenge is not simply to create the data. Rather, it is to collect and analyze it systematically. Doing so ...

Sickle cell disease impacts more than 100,000 people in the United States. It’s estimated that more than two million ...

Would it be a cure for my sickle cell disease? It was a decision I could think about making because my sister was a genetic match and could donate her stem cells. Most with sickle cell don’t ...

Exagamglogene autotemcel (exa-cel) gene therapy offers a potential cure for severe sickle cell disease, now available on NHS.

A new gene editing treatment has been approved for use in the NHS, which will help treat sickle cell disease patients ...

A sickle cell disease “cure” is to be offered to NHS patients for the first time. The £1.65 million gene therapy called exa-cel, also known under the brand name Casgevy, uses a Nobel Prize ...

Individuals with SCT have one copy of the gene associated with sickle cell disease (SCD). SCD is a blood disorder characterized by misshapen blood cells that can cause blockages, leading to ...

Our independent appraisal committee has approved the use of gene editing therapy exagamglogene autotemcel (exa-cel) for use in the NHS in England, providing a potential cure for some people with ...

Despite progress in healthcare services for individuals living with sickle cell disease (SCD) in Africa, substantial gaps ...

Clinical trials for exa-cel have shown promising results that it has been authorised by the FDA and MHRA for use in beta thalassemia and sickle cell disease. These successes make CRISPR technology, as ...