Experts hailed exciting news for some people with sickle cell disease in England as the health watchdog decided to grant ...

A cutting-edge gene therapy has been approved for NHS use for some patients with severe sickle cell disease. Casgevy, also ...

Around 1,700 people could be eligible for the one-time treatment, which is seen as a less risky alternative to a donor stem ...

Cycles of infectious disease prevalence and virulence often reflect natural selection. Sickle Cell disease is an autosomal recessive disorder that causes anemia, joint pain, a swollen spleen ...

Abnormal cells can clog blood vessels, leading to severe pain episodes and restricting oxygen delivery to vital organs ...

People in England with sickle cell will be able to get the world’s first CRISPR-based medicine under an agreement between the ...

A systematic literature review found no evidence to support that physical exertion without rhabdomyolysis (muscle breakdown) or heat injury can cause sudden death for individuals with sickle cell ...

Molecules of sickle-cell hemoglobin stick to one another ... Cystic fibrosis Chromosomal mutation Inversion One region of a chromosome is flipped and reinserted Opitz-Kaveggia syndrome Deletion ...

In 1997, UAB’s Tim Townes, Ph.D., and Thomas Ryan, Ph.D., created the first practical animal model of sickle cell disease, a hereditary blood disorder. Ten years later, Townes, chair of the UAB ...

She wrote most of her examinations on the hospital bed, yet she came out as one of the brightest graduates the University of ...

January 31, 2025 expert reaction to NICE final draft guidance on exagamglogene autotemcel (exa-cel) for severe sickle cell disease . Scientists comment on final draft guidance fro ...

The new gene therapies for sickle cell disease—including the gene-editing treatment Casgevy, based on research at Boston Children's Hospital—have been game-changing for the patients who have ...