The use of an affinity matrix composed of a natural viral receptor or a high-affinity antibody is a much more specific medium for separating viral vectors from host cellular proteins. Figure 1 ...

More information: Russell W. Cochrane et al, High-affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells, Molecular Therapy - Methods & Clinical ...

Rozanolixizumab is a high-affinity humanized immunoglobulin G4 monoclonal antibody and Fc receptor blocker approved to treat ...

Nemvaleukin alfa is an investigational engineered fusion protein composed of modified interleukin-2 (IL-2) and the high-affinity IL-2 alpha receptor chain.

They also show that models learned from nonsynonymous mutations and from out-of-frame sequences are different, prompting new questions about germinal center function. Strengths of the study include an ...

Presentation of phase I data of the early-stage pipeline asset LAD191, a high affinity monoclonal antibody targeting IL-1RaP (interleukin-1 receptor accessory protein), which is expected to impact ...