A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

Unmodified natural killer (NK) cells work differently from the T-cells upon which CAR-T therapies are based – NKs are usually involved in killing cells that are infected with viruses, whereas T ...

Unlike CAR-T cells, NK cells don’t need genetic modification to recognize a specific threat — they act broadly without ...

Prof. MENG Guangxun's team from the Shanghai Institute of Immunity and Infection of the Chinese Academy of Sciences, and collaborators, have revealed a novel mechanism whereby a short form of IL-18, ...

The trial investigated escalating doses of the CAR-NK cells and found that patients tolerated even the highest dose given in this trial. The investigators tested these CAR-NK cells alone in 18 ...

Artiva Biotherapeutics, Inc.’s ARTV share price has dipped by 15.00%, which has investors questioning if this is right time ...

So in working with Dr. Dean Lee at Nationwide Children's Hospital in Columbus, Ohio, he was able to create a TGF-β-resistant natural killer cell. And so through using the healthy cells of ...

Dr. Finlay discusses how cellular metabolism affects NK cell responses to tumors and viral infections, highlighting how metabolic engineering can improve NK cell function in challenging ...