To maintain the integrity of the liposome matrix, vials of extended-release epidural morphine sulfate should be gently inverted or swirled and not vigorously shaken just before use. [21] Likewise ...

Study 1 evaluated the pharmacokinetics of extended-release epidural morphine sulfate in the CSF after doses of 2.5–40 mg, with serial CSF collections for some subjects in the 5-, 10-, and 20-mg ...