While this response might serve the organism well in situations of low nutrient availability, reduced CNS insulin action due to impaired signal transduction could potentially contribute to weight ...

Dopamine receptors bind dopamine, insulin receptors bind insulin ... These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing ...

This heightened activity disrupts normal insulin signaling ... drawing parallels to other signal transduction processes like phosphorylation. This discovery challenges the conventional view ...

Insulin also has a role in the modulation of longevity, mediated via one of the insulin-like growth factor 1 receptor (IGF1-R) signal transduction pathways. The Caenorhabditis elegans IGF1-R homolog ...

Among the key findings is evidence that insulin functions not only as a peripheral regulator of nutrient storage and release of circulating substrates but as a key afferent signal to the CNS for ...