If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

G-protein coupled receptors regulate hormone secretions in ... levels that stems from the decreased secretion and/or action of insulin. Two major forms of diabetes exist, type 1 and type 2.

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.