The Scientist10mon
Insulin mimetics foil obesity
show that small molecule insulin mimetics can reduce food intake and body weight and prevent development of obesity in an animal model.
Nature10y
Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice
The homeostasis model assessment of insulin resistance (HOMA-IR ... The beneficial effects of small-molecule-mediated inhibition of the CD40-TRAF6 interaction in DIO appears to be more pronounced ...
Science Daily26d
Researchers identify molecular glues that protect insulin-producing cells from damage related to diabetes
Researchers have discovered a novel approach to protecting insulin-producing beta cells ... identify and develop small molecules -- termed "molecular glues" -- that enhance the interaction between ...