Hyperalgesia takes your pain and makes it ... which is believed to be an underlying mechanism of fibromyalgia, ME/CFS, and several other conditions. "Central" indicates the central nervous system ...

The Central Nervous System and Pain Perception The central nervous system (CNS), comprising the brain and spinal cord, plays a crucial role in how the body perceives pain. Under normal circumstances, ...

Some of the central molecular mechanisms that lead to hyperalgesia and allodynia after peripheral tissue injury involve the spinal dorsal horn transient receptor potential vanilloid 1 (TRPV1).