Sickle cell disease is a genetic disorder that causes lifelong suffering—here's what you need to know
Hemoglobin is made up of four proteins organized around the iron-carrying heme group. These proteins ... Sickle cell disease changes adult beta-globin. Instead of two alpha and two healthy beta ...
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Genetic correction of sickle cell disease: Insights using transgenic mouse models
Figure 2: Immunofluorescence staining of AγSAD mice RBCs with antibody against γ globin chain. We also assessed various hematologic parameters in these mice. Hemoglobin levels were similar in ...