A traumatic blow to the stomach—from a car accident or fall, for example—is the most common cause of a ruptured spleen. In some cases, a spleen enlarged due to illness can rupture spontaneously.

Many things can cause itching. With PV ... About 3 out of 4 people with PV have an enlarged spleen. Doctors call this “splenomegaly.” Gout is a type of arthritis. It's caused by the buildup ...

One consequence of malaria is anaemia, which can cause the spleen to become enlarged. So Bald’s Leechbook suggests that a remedy for an enlarged spleen is: take a very hot iron rod, just out of ...