Hematopoiesis begins in the human embryo after the fourth week in the aorta, close in time and location to the cardiac anlage. Building on their heart organoid model, the researchers gradually ...

it's possible to model hematopoiesis in a system that's already recapitulating aspects of heart development. This is because the hematopoietic, endothelial, and cardiac tissues are all derived from ...

Exploiting their understanding of genetics and hematopoiesis, researchers from the University of Tsukuba have developed a new, embryonic HSC transplantation model that lacks HSCs. They have shown ...