Hematopoiesis begins in the human embryo after the fourth week in the aorta, close in time and location to the cardiac anlage. Building on their heart organoid model, the researchers gradually ...

it's possible to model hematopoiesis in a system that's already recapitulating aspects of heart development. This is because the hematopoietic, endothelial, and cardiac tissues are all derived from ...

This finding underscores how a transcription factor traditionally associated with hematopoiesis can be ... have enabled the generation of human embryonic stem cell lines that express tagged ...