"We found that the manner in which tumor cells die after radiotherapy depends on the engagement of specific DNA repair pathways, particularly when radiation is given at very high, focused doses.

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the ...

For this reason, they are at greater risk of accumulating damage and must develop alternative repair pathways to avoid dysfunction. Scientists do not understand how neuronal DNA damage is ...

How do we find out which protein works in a particular DNA repair pathway? We know that if a DNA repair gene is mutated, cells become more sensitive to DNA damaging agents. Researchers in the ...

“We found that the manner in which tumour cells die after radiotherapy depends on the engagement of specific DNA repair pathways, particularly when radiation is given at very high, focussed dose ...

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the World Health Organization ...

He, who was recently appointed as Bloomberg Distinguished Professor of Structural Biophysics and Chromatin Biology at Johns Hopkins University, explores how flaws in the transcription and DNA repair ...

Phosphoproteomics unveils the mode of action of clinical ATR inhibitors and explains their synergy with Gemcitabine in ...

PARylation is integral to many key cellular functions, including signaling modulation and DNA repair. PARylation is reversible and is undone by PAR erasers such as poly ADP-ribose glycohydrolase (PARG ...

New research from Tulane University has identified a unique genetic signature in bacteria that can predict their likelihood of developing antibiotic resistance, a finding that can help quickly ...