Cystic fibrosis is a chronic genetic disease affecting both the lungs ... This leads to the premature termination of mRNA sequence; 2%–5% of cystic fibrosis is caused by class 1 dysfunction.

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the ...

Viral and nonviral clinical trials have established proof-of-principle for gene transfer into the cystic fibrosis (CF) lung. It is currently unknown whether gene transfer efficiency is sufficient ...

Using the Human Genome Sequence to Study Disease ... For example, cystic fibrosis is typically characterized as a single-gene disease associated with recessive mutations in the CFTR gene.

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the ...

and we hope future research could lead to the development of genetic therapy treatments for those with rarer CF mutations too,” said Lucy Allen, a lung biologist and research director at Cystic ...

An explanation of the cause and effects of the genetic disorder cystic fibrosis and how it can be treated using gene therapy. There is a discussion about gene therapy which includes an interview ...

Cystic fibrosis (CF) is a single-gene disorder with insufficient treatment options and a target organ, the lung that is relatively easily accessible. Thus, it is not surprising that in the early ...

An explanation of the cause and effects of the genetic disorder cystic fibrosis and how it can be treated using gene therapy. There is a discussion about gene therapy which includes an interview ...