TMEM16A (ANO1): A specific type of calcium-activated chloride channel that is involved in various physiological processes and has been implicated in several diseases. Cystic Fibrosis: A genetic ...
Cystic fibrosis (CF ... This protein acts as a channel that transports negatively charged particles called chloride ions in ...
They do not have enough abnormal chloride channels to cause the labored breathing and clogged pancreas of cystic fibrosis, but they do have enough of a defect to prevent the cholera from taking hold.
Ivacaftor is a new CFTR potentiator that helps the CFTR channel ... CFQ-R = Cystic Fibrosis Questionnaire-Revised; FEV 1 = forced expiratory volume in 1 second. Mean change in sweat chloride ...
A novel once-daily drug showed a comparable efficacy and safety profile as the standard-of-care drug in patients with cystic ...
Patients aged 6 to 11 years with cystic fibrosis receiving 24-week once-daily vanzacaftor/tezacaftor/deutivacaftor generally ...
Cystic fibrosis is ... surface of a cell. Ion channels are like gates in a cell’s membrane that allow certain molecules to pass through. CFTR usually makes a gate for chloride ions, a type ...