In most recent advancements, RNA editing uses the CRISPR-Cas13 system, a newer technique that was created specifically to help develop therapies that work with RNA. DNA editing is permanent, which ...
Editing RNA isn’t all that different from DNA base-editing techniques, which typically use Cas9 or other enzymes attached to a CRISPR guide RNA to replace one nucleotide ... attached to another ...
Type VI Cas13 is atypical in that it uses guide and target RNAs to cleave substrate ... triggers innate antiviral immune responses. 5’-ppp-RNA Recognition by RIG-I. We have solved the crystal ...
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