A popular hypothesis for how the brain clears molecular waste, which may help explain why sleep feels refreshing, is a ...

Research led by Charité–Universitätsmedizin Berlin has found that metal particles from artificial joint implants can enter ...

The brain is an organ surrounded by the skull and an elaborate protective system, and receives nutrients from the blood through the blood-brain barrier. However, the brain is one of the organs ...

Scientists suggest study findings could point to the future development of new treatments for age-related cognitive decline.

A CSF leak occurs when cerebrospinal fluid (CSF) escapes from the protective layer surrounding the brain and spinal cord. This is a serious condition that can cause headaches, seizures, or meningitis.

First described by Nedergaard and her colleagues in 2012, the glymphatic system is the brain's unique waste removal process that uses cerebrospinal fluid (CSF) to wash away excess proteins ...

A cholesterol receptor protein called LDLR appears to be a key driver of neurotoxicity in sporadic ALS, per new research ...

Protective borders between the brain and the blood weaken with age. This includes the barrier formed by tightly linked epithelial cells in the choroid plexus, which generates cerebrospinal fluid. In ...

A decade ago, Kipnis' lab discovered a network of vessels surrounding the brain -- known as the meningeal lymphatics -- in mice and humans that drains fluid and waste into the lymph nodes, where many ...

Every night, while the body rests, the brain orchestrates a vital cleanup operation. Cerebrospinal fluid, which bathes the ...

Tony Wyss-Coray and colleagues performed large-scale protein analyses of cerebrospinal fluid, the fluid that surrounds the brain and spinal cord, from a total of 3,397 people in six independent ...