A popular hypothesis for how the brain clears molecular waste, which may help explain why sleep feels refreshing, is a ...

In experiments with mice that can switch the production of neurotransmitters during non-REM sleep, it was confirmed that the amount of cerebrospinal fluid in the brain increases when the ...

However, new research in mice demonstrates that ... the glymphatic system is the brain's unique waste removal process that uses cerebrospinal fluid (CSF) to wash away excess proteins generated ...

Research led by Charité–Universitätsmedizin Berlin has found that metal particles from artificial joint implants can enter ...

This includes the barrier formed by tightly linked epithelial cells in the choroid plexus, which generates cerebrospinal fluid. In the February 26 Neuron ... into the aging mouse brain, and when they ...

Scientists suggest study findings could point to the future development of new treatments for age-related cognitive decline.

The researchers found that zolpidem diminished norepinephrine oscillations in mice, reducing cerebrospinal fluid flow. This ...

A CSF leak occurs when cerebrospinal fluid (CSF) escapes from the protective layer surrounding the brain and spinal cord. This is a serious condition that can cause headaches, seizures ...

A cholesterol receptor protein called LDLR appears to be a key driver of neurotoxicity in sporadic ALS, per new research ...

Tony Wyss-Coray and colleagues performed large-scale protein analyses of cerebrospinal fluid, the fluid that surrounds the brain and spinal cord, from a total of 3,397 people in six independent ...

A decade ago, Kipnis' lab discovered a network of vessels surrounding the brain -- known as the meningeal lymphatics -- in mice and humans that drains fluid and waste into the lymph nodes, where many ...

They found the presence of higher levels of KIBRA in cerebrospinal fluid and lower levels ... being affected by tau in the brain.” With these findings, the team then decided to test the correlation on ...