Complementary discoveries have the potential to enhance treatment options for antibiotic-resistant infections. Researchers at ...

Yet others, called base editors, change one letter of the DNA code to another. So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to ...

For this reason, compared with all previously available methods, it is much easier to ‘program’ CRISPR-Cas9 at a particular cutting point on the DNA strand. Various types of endonucleases – enzymes ...

The core components of CRISPR-based genome-editing ... To find out, Zhang's team used a specialized type of mass spectrometry to identify and analyze the Cas9 and Cas 12 protein fragments ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

Cas enzymes are required to cut specific sections of DNA or RNA during CRISPR experiments. CRISPR is a revolutionary gene-editing tool widely used for cancer research, which is currently in the ...

CRISPR sequences—short snippets of DNA ... by engineering customizable short guide RNA to direct the enzymes to introduce cuts at specific points in the genome. Cas9, the first Cas protein repurposed ...

In gene and cell therapy, RNP-mediated CRISPR gene editing is quickly emerging as the new norm. For many gene editing firms, GenScript has created hundreds of Cas9, Cas12a, Cas13a, MAD7 ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.