CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

Bring up germline editing, and most scientists cringe. The idea behind the notorious CRISPR-baby scandal, editing reproductive cells or embryos tinkers with DNA far beyond just the patient—any changes ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

Treatments for rare diseases are hard to create and expensive to deliver, but there is new hope for editing the software of the ... fiction a few years ago. Then Crispr came along—the elegant ...

CRISPR Therapeutics' stock decline is likely influenced by Editas Medicine's struggles, but CRISPR remains a distinct and stronger company with a promising long-term outlook. CRISPR's strategic ...

"As CRISPR therapies enter the clinic ... Zhang's lab used prediction software to validate that the new nucleases were less likely to trigger immune responses. Next, the team engineered a panel ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Winston Yan’s graduate school project involved using a variant of the CRISPR-Cas9 genome editing system to knock down a gene that regulates cholesterol in mice. “The real goal was to eventually pave ...