Scientists have successfully engineered the most complicated human cell lines ever, indicating that our genomes are more tolerant to significant structural alterations than previously ...

Two decades later, thanks to massive improvements in gene sequencing and synthesis technologies alongside the rise of gene editing multitool CRISPR, gene therapy is no longer science fiction. In late ...

As sequencing technology becomes ubiquitous, scientists take their research to new heights by implementing novel methods. Download this ebook from The Scientist to learn about Pairing CRISPR screening ...

Using genome sequencing, they were able to analyze the ... In a new study, the team used a combination of CRISPR prime editing and human cell lines—groups of human cells in a dish—to generate ...

However, accurate prediction of CRISPR-Cas9 off-target sites and activity is challenging. We have developed a new protocol for detection of gRNA binding and Cas9 cleavage, based on amplification-free ...

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.

Thermo Fisher Scientific, Horizon Discovery, OriGene Technologies, QIAGEN, and GeneCopoeia Lead the Competition MicroRNA ...

Visualizing cells after editing specific genes can help scientists learn new details about the function of those genes. But ...

In July 2023, Sanofi expanded an existing partnership with Scribe Therapeutics to use its CRISPR-based gene-editing technology to develop both in vivo and ex vivo cancer cell therapies.

CRISPR Therapeutics' stock decline is likely influenced by Editas Medicine's struggles, but CRISPR remains a distinct and stronger company with a promising long-term outlook. CRISPR's strategic ...

Functional genomics can help deconvolute the link between genotype and phenotype in disease, revealing new drug targets and ...

The CEP290 gene is too big to be carried by viral vectors, but using CRISPR its sequence can be edited to restore its normal function, by snipping out a small section. Allergan licensed rights to ...