The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease.

A second wave of CRISPR-based methods that work by boosting or dampening gene-expression levels, rather than cutting genes, has made the tool even more useful. Together, these techniques are more than ...

thanks to massive improvements in gene sequencing and synthesis technologies alongside the rise of gene editing multitool CRISPR, gene therapy is no longer science fiction. In late 2023, the UK ...

In July 2023, Sanofi expanded an existing partnership with Scribe Therapeutics to use its CRISPR-based gene-editing technology to develop both in vivo and ex vivo cancer cell therapies.

leading to the first FDA-approved CRISPR-based gene editing treatment, Casgevy. Editas' discontinuation of its SCD and TDT program and significant layoffs highlight its precarious position ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) ...

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.