A research group at Umeå University has developed new advanced light-controlled tools that enable precise control of proteins ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

Typically, for Cas9 to bind and cleave a target DNA sequence ... genomes of living cells.” “[These findings] can provide an additional mechanism by which off-target cuts are being recruited in cells ...

High-throughput measurement of cellular traction forces at the nanoscale remains a significant challenge in mechanobiology, limiting our understanding of how cells interact ... forces using DNA ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

If you took a glance around Anthony James’s office, it wouldn’t be hard to guess what he does for a living ... CRISPR in an attempt to eliminate HIV from the DNA of human cells.

How do these records provide information about the environment outside the cell? We’re quite fortunate in that evolution endowed bacteria with a plethora of sensors ... DNA or RNA, and then the ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more ...

with the goal of engineering a decentralized CRISPR-based NAAT solution that can be used by anyone without the need for complex laboratory instruments. We have designed, developed, and validated a ...

In theory, CRISPR gene editing could be used to make any modification to the DNA of virtually any living being. While we think first ... application is treating genetic diseases such as sickle cell ...

Genomes can now be entrusted to store information about a variety of transient biological events inside of living cells ... in the CRISPR field for developing both the ENGRAM and DNA Typewriter ...