The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

2 The team next wanted to test these findings in a physiological context; they were curious to see how negative supercoiling, or under twisting of DNA that happens during normal transcription and ...

CRISPR places an entirely new kind of power into human hands. For the first time, scientists can quickly and precisely alter, delete, and rearrange the DNA of nearly any living organism ...

Early reports have demonstrated that CRISPR effectively excises integrated human immunodeficiency virus type 1 (HIV) from cells. 1,2 For Michele Lai from the University of Pisa, these studies raised ...