Researchers using CRISPR-Cas9 gene editing tools have discovered that while ... system that uses an impaired Cas protein to chauffeur enzymes that create single point mutations, such as swapping an ...

Her Doudna Lab team at Berkeley has also corrected the genetic mutation that causes sickle cell disease using CRISPR-Cas9. Some scientists warn about the ethical dangers of using gene editing in ...

Base editing to get cell therapies on point While a traditional CRISPR-Cas9 platform cleaves both ... including pre-clinical correction of gene mutations underlying progeria, glycogen storage ...

This technique utilizes the CRISPR-Cas9 system, known for its ability ... pylori infections, is often caused by point mutations in the 23S ribosomal RNA coding gene of the bacterium.

The standard Cas9 protein cuts the DNA at the target. When the cut is repaired, mutations are introduced that usually disable a gene. This is by far the most common use of CRISPR. It’s called ...

CRISPR-Cas genome editing can repair natural mutations in plants, as demonstrated in tomatoes, leading to earlier yields. This precise method contrasts with traditional, random mutagenesis techniques.