Horizon has created a library of ready-made isogenic human cell line pairs edited using CRISPR-Cas9 technology. With 10,000 gene targets available — 3,000 of them off-the-shelf — the knockout ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

Jim Cramer, the host of Mad Money, reflected on the uncertainty surrounding the year 2025, focusing on several macroeconomic ...

Both gene knockout and knock-in models are powerful ... regularly interspaced short palindromic repeats (CRISPR)/associated ...

CRISPR uses an enzyme known as Cas9 to cut and alter DNA ... ultrasound-controllable CRISPR toolbox to knock out, activate, or silence a specific gene," Liu said. "Combining that with ...

“So we decided to work only with Cas9 and the RNA guide, and these work wonderfully.” With DIPA-CRISPR, the researchers inject a commercially available Cas9 enzyme and guide RNA into the haemocoel—the ...

Advances in CRISPR technologies promise to accelerate the burgeoning pipeline of gene-editing therapies and broaden access to these disease-altering therapies.

Most recently, CRISPR-Cas9 based ‘knock-out’ of two genes in tomato plants increased their sweetness with no loss in weight. Similar studies on other plants and fruits will surely follow.

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...