Get Instant Summarized Text (Gist) CRISPR nucleases, Cas9 and Cas12, have been engineered to evade immune detection, addressing a key challenge in CRISPR-based therapies. By identifying and ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating ...

Advances in CRISPR technologies promise to accelerate the burgeoning pipeline of gene-editing therapies and broaden access to these disease-altering therapies.

Base editing (BE) is a CRISPR-Cas9-based genome editing technology that allows the ... Explain the main differences between BE & PE Systems. 3. Discuss applications of BE and PE systems.

9 In addition to its application in infectious diseases, there are several CRISPR-based developments for the diagnosis of other diseases, including cancer, where it is being used to detect cancer ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modelling and interrogating human disease.

Casgevy (exagamglogene autotemcel or exa-cel) became the first drug based on the CRISPR/Cas9 gene-editing technology ... The one-shot therapy is an ex vivo application of the technology, meaning ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease.

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

Innovative synthetic biology techniques are revolutionizing microbiota-based therapies, enhancing microbial functions for ...

Among the most exciting breakthroughs are gene therapy and gene editing, with CRISPR-Cas9 leading the charge ... but seeming far from real-world applications. Just six years later, after earning ...