Adrenaline is commonly associated with the "flight or fight" response. It most commonly originates from cells in the adrenal gland, but can, in rare cases, originate from nodules outside the adrenal ...

ACTH is the only naturally occurring agonist for the ACTH receptor, which is principally expressed in cells of the adrenal cortex. This receptor signals the cells in the zona fasciculata of the ...

There are multiple proteins which, when incorrectly coded by DNA, can cause the breakdown of this loop. MC2R encodes the receptor in the adrenal cells that interact with ACTH. If the receptor is ...

Sexual precocity and a testicular mass can result from a Leydig cell tumor or from simple virilizing CAH with adrenal rests in the testes. These diagnoses are usually distinguished by very high ...