The Huskies are back in the Final Four for the 16 th time in the last 17 years. They won Region 4 with a 78-64 victory over USC in the Elite 8. The All-America Bueckers led UConn

Oddly enough, the Alamodome was also the venue the only other time all four No. 1 seeds made the Final Four. In 2008, Kansas toppled Memphis in overtime to win Bill Self’s first national title, tying the game in the final seconds of regulation with a Mario Chalmers 3-pointer after Derrick Rose missed a potential clinching free throw.

The Final Four is days away as all four No. 1 seeds head to San Antonio for the chance to win a national championship.

Final Four picks, predictions, odds explain why Houston Cougars will beat Duke Blue Devils in NCAA Tournament March Madness game Saturday, April 5.

The Auburn Tigers and Florida Gators meet in an all-SEC clash to kick off the Final Four on Saturday. Then, the Duke Blue Devils square off with the Houston Cougars in the nightcap in San Antonio. Each battle between No. 1 seeds could produce games that are talked about for decades.

Which team will be 2025 men's college basketball national champion? What Final Four picks, odds say about Duke, Houston, Auburn, Florida's chances.

Final Four picks, predictions, odds explain why Florida Gators will beat Auburn Tigers in NCAA Tournament March Madness game Saturday, April 5, 2025.

ESPN's Jay Bilas received quite a bit of flack for picking all four one-seeds to make the Final Four in his NCAA tournament bracket. He may have had a crystal ball, however, as each No. 1 won their region and will meet in San Antonio to determine this season's champion.